Identification
Name:Monofunctional biosynthetic peptidoglycan transglycosylase
Synonyms:Not Available
Gene Name:mtgA
Enzyme Class:Not Available
Biological Properties
General Function:regulation of cell shape
Specific Function:Cell wall formation.
Cellular Location:Not Available
SMPDB Pathways:
KEGG Pathways:
SMPDB Reactions:
2.0Thumb1.0Thumb+1.0Thumb+1.0 a peptidoglycan dimer (meso-diaminopimelate containing)
2.0lipid II(A) → 1.0Undecaprenyl diphosphate + 1.0Hydrogen ion + 1.0 a peptidoglycan dimer (meso-diaminopimelate containing)
ReactionCard
2.0Thumb1.0 a peptidoglycan dimer (meso-diaminopimelate containing)+1.0Thumb+1.0Thumb
Metabolites:
ECMDB IDNameView
ECMDB21225Hydrogen ionMetaboCard
ECMDB23023lipid II(A)MetaboCard
ECMDB01469Undecaprenyl diphosphateMetaboCard
ECMDB20210Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-D-glutaminyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanineMetaboCard
GO Classification:
Function
cell wall organization
Gram-negative-bacterium-type cell wall biogenesis
integral component of membrane
peptidoglycan biosynthetic process
peptidoglycan glycosyltransferase activity
peptidoglycan-based cell wall
plasma membrane
regulation of cell shape
transferase activity, transferring pentosyl groups
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>729
atgagtaaaagccgcttaacggtgtttagtttcgttcgccgttttcttttgcggttaatg
gttgtcctcgccgttttctggggcgggggcatcgcgttgtttagcgttgcgcctgttccc
ttctcagcggtaatggtcgagcgacaggtcagcgcctggctgcatggcaattttcgttac
gtggcacattctgactgggtcagtatggatcaaatctcgccgtggatgggactggcggtg
attgccgcagaagatcagaaatttcctgagcactggggctttgatgtcgcttccattgag
aaagccctggcgcacaacgagcgcaatgaaaaccgtattcgcggtgcttcaacgatttct
caacagacagccaaaaatctctttttatgggatgggcgtagctgggttcgaaaagggctg
gaagccggattaacgctggggatagaaacggtctggagcaaaaagcgtatcctgacggtt
tacctgaatatcgccgaatttggcgacggtgtgtttggcgtcgaagctgcggcacaacgt
tatttccacaaacccgcgagcaaacttacccggtcggaagctgcattactggcagctgta
ttacctaatccacttcgtttcaaagtctcctcgccatcgggctacgtgcgtagccgtcag
gcgtggattttacggcagatgtatcagttaggcggtgagccgtttatgcaacaacaccag
ctggattaa
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:242
Protein Molecular Weight:27341
Protein Theoretical pI:Not Available
Signaling Regions:Not Available
Transmembrane Regions:
  • 19-39
Protein Sequence:
>Monofunctional biosynthetic peptidoglycan transglycosylase
MSKSRLTVFSFVRRFLLRLMVVLAVFWGGGIALFSVAPVPFSAVMVERQVSAWLHGNFRY
VAHSDWVSMDQISPWMGLAVIAAEDQKFPEHWGFDVASIEKALAHNERNENRIRGASTIS
QQTAKNLFLWDGRSWVRKGLEAGLTLGIETVWSKKRILTVYLNIAEFGDGVFGVEAAAQR
YFHKPASKLTRSEAALLAAVLPNPLRFKVSSPSGYVRSRQAWILRQMYQLGGEPFMQQHQ
LD
References
External Links:
ResourceLink
Uniprot ID:P46022
Uniprot Name:MTGA_ECOLI
CCDB:MTGA_ECOLI
General Reference:Not Available