Identification
Name:Lipopolysaccharide core biosynthesis protein rfaZ
Synonyms:Not Available
Gene Name:rfaZ
Enzyme Class:Not Available
Biological Properties
General Function:Involved in lipopolysaccharide biosynthetic process
Specific Function:Specific function unknown
Cellular Location:Not Available
SMPDB Pathways:
KEGG Pathways:
  • Lipopolysaccharide biosynthesis ec00540
EcoCyc Reactions:
1.0a lipopolysaccharide+1.0Thumb ? 1.0KDOIII-lipopolysaccharide+1.0Thumb
1.0a lipopolysaccharide + 1.0CMP-3-Deoxy-D-manno-octulosonate ? 1.0KDOIII-lipopolysaccharide + 1.0Cytidine monophosphate
ReactionCard
Complex Reactions:
1.0Thumb+1.0Thumb1.0Thumb+1.0Thumb+1.0Thumb
Metabolites:
ECMDB IDNameView
ECMDB20133CMP-3-Deoxy-D-manno-octulosonateMetaboCard
ECMDB00095Cytidine monophosphateMetaboCard
ECMDB21225Hydrogen ionMetaboCard
ECMDB21343Kdo-phospho-heptosyl-phospho-heptosyl-heptosyl-kdo2-lipidAMetaboCard
ECMDB21351Phospho-heptosyl-phospho-heptosyl-heptosyl-kdo2-lipidAMetaboCard
GO Classification:Not Available
Gene Properties
Blattner:b3624
Gene OrientationCounterclockwise
Centisome Percentage:81.85
Left Sequence End3797368
Right Sequence End3798219
Gene Sequence:
>852 bp
ATGGCTGAAATTACCGCATCCCTGGTAAAAGAGCTGCGTGAGCGTACTGGCGCAGGCATG
ATGGATTGCAAAAAAGCACTGACTGAAGCTAACGGCGACATCGAGCTGGCAATCGAAAAC
ATGCGTAAGTCCGGTGCTATTAAAGCAGCGAAAAAAGCAGGCAACGTTGCTGCTGACGGC
GTGATCAAAACCAAAATCGACGGCAACTACGGCATCATTCTGGAAGTTAACTGCCAGACT
GACTTCGTTGCAAAAGACGCTGGTTTCCAGGCGTTCGCAGACAAAGTTCTGGACGCAGCT
GTTGCTGGCAAAATCACTGACGTTGAAGTTCTGAAAGCACAGTTCGAAGAAGAACGTGTT
GCGCTGGTAGCGAAAATTGGTGAAAACATCAACATTCGCCGCGTTGCTGCGCTGGAAGGC
GACGTTCTGGGTTCTTATCAGCACGGTGCGCGTATCGGCGTTCTGGTTGCTGCTAAAGGC
GCTGACGAAGAGCTGGTTAAACACATCGCTATGCACGTTGCTGCAAGCAAGCCAGAATTC
ATCAAACCGGAAGACGTATCCGCTGAAGTGGTAGAAAAAGAATACCAGGTACAGCTGGAT
ATCGCGATGCAGTCTGGTAAGCCGAAAGAAATCGCAGAGAAAATGGTTGAAGGCCGCATG
AAGAAATTCACCGGCGAAGTTTCTCTGACCGGTCAGCCGTTCGTTATGGAACCAAGCAAA
ACTGTTGGTCAGCTGCTGAAAGAGCATAACGCTGAAGTGACTGGCTTCATCCGCTTCGAA
GTGGGTGAAGGCATCGAGAAAGTTGAGACTGACTTTGCAGCAGAAGTTGCTGCGATGTCC
AAGCAGTCTTAA
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:283
Protein Molecular Weight:32920
Protein Theoretical pI:10
Signaling Regions:
  • None
Transmembrane Regions:
  • None
Protein Sequence:
>Lipopolysaccharide core biosynthesis protein rfaZ
MKNIRYIDKKDVENLIENKISDDVIIFLSGPTSQKTPLSVLRTKDIIAVNGSAQYLLSNN
IVPFIYVLTDVRFLHQRRDDFYKFSQRSRYTIVNVDVYEHASKEDKLYILQNCLVLRSFY
RREKGGFIKKIKFNILRQIHKELLISVPLSKKGRLVGFCKDISLGYCSCHTIAFAAIQIA
YSLKYARIICSGLDLTGSCSRFYDENKNPMPSELSRDLFKILPFFRFMHDNVKDINIYNL
SDDTAISYDVIPFIKLQDISAEESKDMTRKKMQYRTSTDSYAN
References
External Links:
ResourceLink
Uniprot ID:P27241
Uniprot Name:RFAZ_ECOLI
GenBank Gene ID:AP009048
Genebank Protein ID:21239025
Ecogene ID:EG11426
Ecocyc:EG11426
ColiBase:b3624
Kegg Gene:b3624
EchoBASE ID:EB1396
CCDB:RFAZ_ECOLI
BacMap:16131495
General Reference:
  • Blattner, F. R., Plunkett, G. 3rd, Bloch, C. A., Perna, N. T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J. D., Rode, C. K., Mayhew, G. F., Gregor, J., Davis, N. W., Kirkpatrick, H. A., Goeden, M. A., Rose, D. J., Mau, B., Shao, Y. (1997). "The complete genome sequence of Escherichia coli K-12." Science 277:1453-1462. Pubmed: 9278503
  • Hayashi, K., Morooka, N., Yamamoto, Y., Fujita, K., Isono, K., Choi, S., Ohtsubo, E., Baba, T., Wanner, B. L., Mori, H., Horiuchi, T. (2006). "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Mol Syst Biol 2:2006.0007. Pubmed: 16738553
  • Klena, J. D., Pradel, E., Schnaitman, C. A. (1992). "Comparison of lipopolysaccharide biosynthesis genes rfaK, rfaL, rfaY, and rfaZ of Escherichia coli K-12 and Salmonella typhimurium." J Bacteriol 174:4746-4752. Pubmed: 1624462
  • Sofia, H. J., Burland, V., Daniels, D. L., Plunkett, G. 3rd, Blattner, F. R. (1994). "Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes." Nucleic Acids Res 22:2576-2586. Pubmed: 8041620