Identification
Name:nitroreductase A, NADPH-dependent, FMN-dependent (EC:1.-.-.-)
Synonyms:Not Available
Gene Name:nfsA
Enzyme Class:Not Available
Biological Properties
General Function:Not Available
Specific Function:Not Available
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:
KEGG Reactions:
1.0Trinitrotoluene+2.0Thumb+2.0Thumb1.04-Hydroxylamino-2,6-dinitrotoluene+2.0Thumb+1.0Thumb
1.0Trinitrotoluene + 2.0NADPH + 2.0Hydrogen ion ↔ 1.04-Hydroxylamino-2,6-dinitrotoluene + 2.0NADP + 1.0Water
ReactionCard
1.0Trinitrotoluene+2.0Thumb+2.0Thumb1.04-Hydroxylamino-2,6-dinitrotoluene+2.0Thumb+1.0Thumb
1.0Trinitrotoluene + 2.0NADH + 2.0Hydrogen ion ↔ 1.04-Hydroxylamino-2,6-dinitrotoluene + 2.0NAD + 1.0Water
ReactionCard
1.0Trinitrotoluene+2.0Thumb+2.0Thumb1.02-Hydroxylamino-4,6-dinitrotoluene+2.0Thumb+1.0Thumb
1.0Trinitrotoluene + 2.0NADH + 2.0Hydrogen ion ↔ 1.02-Hydroxylamino-4,6-dinitrotoluene + 2.0NAD + 1.0Water
ReactionCard
Metabolites:
ECMDB IDNameView
ECMDB21225Hydrogen ionMetaboCard
ECMDB00902NADMetaboCard
ECMDB01487NADHMetaboCard
ECMDB00217NADPMetaboCard
ECMDB04111NADPHMetaboCard
ECMDB00494WaterMetaboCard
GO Classification:Not Available
Gene Properties
Blattner:b0851
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>eco:b0851 nfsA; nitroreductase A, NADPH-dependent, FMN-dependent (EC:1.-.-.-); K10678 nitroreductase [EC:1.-.-.-] (N)
ATGACGCCAACCATTGAACTTATTTGTGGCCATCGCTCCATTCGCCATTTCACTGATGAA
CCCATTTCCGAAGCGCAGCGTGAGGCGATTATTAACAGCGCCCGTGCGACGTCCAGTTCC
AGTTTTTTGCAGTGCAGTAGCATTATTCGCATTACCGACAAAGCGTTACGTGAAGAACTG
GTGACGCTGACCGGCGGGCAAAAACACGTAGCGCAAGCGGCGGAGTTCTGGGTGTTCTGT
GCCGACTTTAACCGCCATTTACAGATCTGTCCGGATGCTCAGCTCGGCCTGGCGGAACAA
CTGTTGCTCGGTGTCGTTGATACGGCAATGATGGCGCAGAATGCATTAATCGCAGCGGAA
TCGCTGGGATTGGGCGGGGTATATATCGGCGGCCTGCGCAATAATATTGAAGCGGTGACG
AAACTGCTTAAATTACCGCAGCATGTTCTGCCGCTGTTTGGGCTGTGCCTTGGCTGGCCT
GCGGATAATCCGGATCTTAAGCCGCGTTTACCGGCCTCCATTTTGGTGCATGAAAACAGC
TATCAACCGCTGGATAAAGGCGCACTGGCGCAGTATGACGAGCAACTGGCGGAATATTAC
CTCACCCGTGGCAGCAATAATCGCCGGGATACCTGGAGCGATCATATCCGCCGAACAATC
ATTAAAGAAAGCCGCCCATTTATTCTGGATTATTTGCACAAACAGGGTTGGGCGACGCGC
TAA
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:Not Available
Protein Molecular Weight:Not Available
Protein Theoretical pI:Not Available
Signaling Regions:Not Available
Transmembrane Regions:Not Available
Protein Sequence:
>eco:b0851 nfsA; nitroreductase A, NADPH-dependent, FMN-dependent (EC:1.-.-.-); K10678 nitroreductase [EC:1.-.-.-] (A)
MTPTIELICGHRSIRHFTDEPISEAQREAIINSARATSSSSFLQCSSIIRITDKALREEL
VTLTGGQKHVAQAAEFWVFCADFNRHLQICPDAQLGLAEQLLLGVVDTAMMAQNALIAAE
SLGLGGVYIGGLRNNIEAVTKLLKLPQHVLPLFGLCLGWPADNPDLKPRLPASILVHENS
YQPLDKGALAQYDEQLAEYYLTRGSNNRRDTWSDHIRRTIIKESRPFILDYLHKQGWATR
References
External Links:
ResourceLink
Uniprot ID:P17117
ColiBase:b0851
Kegg Gene:b0851
EchoBASE ID:EB1241
BacMap:16128819
General Reference:Not Available