Identification
Name:Translocation and assembly module TamA
Synonyms:Not Available
Gene Name:tamA
Enzyme Class:Not Available
Biological Properties
General Function:protein secretion
Specific Function:Part of the translocation and assembly module (TAM) autotransporter assembly complex, which functions in translocation of autotransporters across the outer membrane. Has anion selective channel-forming ability, but the physiological relevance of this activity is unclear.
Cellular Location:Not Available
SMPDB Pathways:Not Available
KEGG Pathways:Not Available
Metabolites:
ECMDB IDNameView
GO Classification:
Function
cell outer membrane
integral component of cell outer membrane
protein secretion
TAM protein secretion complex
Gene Properties
Blattner:Not Available
Gene OrientationNot Available
Centisome Percentage:Not Available
Left Sequence EndNot Available
Right Sequence EndNot Available
Gene Sequence:
>1734
gtgcgctatatccgacagttatgctgtgtaagcttactctgcttaagcggatctgccgtc
gccgcgaacgtccgtctacaggtcgaggggttatcgggacagctggaaaagaacgttcgt
gcgcagctttctacgattgaaagtgatgaagtgacgccagaccgtcgctttcgcgcacgc
gtcgatgatgccatccgcgaaggtctgaaagcgctgggttattaccagccgaccattgaa
tttgatctccgtccaccgccaaagaaagggcggcaggtattgatcgccaaagtcacgcca
ggcgtgccggtgttaattggcggcaccgatgtggtattgcgcggcggcgcgcggaccgat
aaagactatttgaaattgctcgatactcgcccggctattggcacggtactgaaccagggc
gattatgaaaatttcaaaaagtccttaaccagcattgcgttgcgtaaaggttatttcgat
agcgaatttaccaaagcgcagctgggcattgcgctcggcctgcataaagccttctgggat
attgattataacagtggcgaacgttaccgctttgggcatgtgacctttgaaggatcacaa
atccgcgatgaatacctgcaaaatctggtgccgtttaaagagggcgatgagtacgaatcg
aaagatctggcagaactgaaccgccgactttctgctaccggctggtttaactcggtggtg
gtggctccacaatttgataaagcgcgcgaaacgaaagtattaccattgacgggcgtggtt
tcgccgcgaacagaaaacaccatcgaaaccggggtcggttactctacggacgtgggaccg
cgcgtgaaagcgacgtggaaaaagccgtggatgaactcttatggtcacagtctgaccacc
agtactagtatttccgcgccggaacagaccctcgacttcagctataaaatgccgctgctg
aagaatccactggaacaatattatttggtgcagggcggttttaagcgcactgacctgaac
gataccgaatctgactccactacgctggtggcttctcgctactgggatctctccagcggc
tggcagcgtgccattaacctgcgctggagtctcgaccactttactcagggtgaaattacc
aataccacgatgctgttttatcctggggtgatgattagccgcacgcgttctcgtggtggc
ctgatgccaacctggggcgactcgcaacgctactctatcgactactccaacacggcctgg
ggttcagatgtcgatttctccgttttccaggcgcagaacgtctggatccgcacactgtac
gatcgccatcgttttgttacacgcggcacgctgggctggattgaaaccggtgatttcgac
aaagtaccgccggatctgcgtttcttcgccgggggcgaccgcagtattcgtggctacaaa
tacaaatctatcgctccgaaatacgccaacggtgacctgaaaggggcctcgaagttgata
accggatcgctggaataccagtacaacgtgaccggaaaatggtggggcgcggtgtttgtc
gatagtggcgaagcggtaagcgatattcgccgcagcgactttaaaaccggtaccggggtc
ggcgtgcgctgggaatcgccggtcgggccaatcaaactcgattttgccgtaccggtcgcg
gataaagacgaacacgggttacagttttacatcggtctggggccagaattatga
Protein Properties
Pfam Domain Function:Not Available
Protein Residues:577
Protein Molecular Weight:64795
Protein Theoretical pI:Not Available
PDB File:2LY3
Signaling Regions:
  • 1-21
Transmembrane Regions:
  • 447-454
  • 465-472
  • 476-483
  • 500-510
  • 514-523
  • 535-544
  • 551-559
  • 567-577
Protein Sequence:
>Translocation and assembly module TamA
MRYIRQLCCVSLLCLSGSAVAANVRLQVEGLSGQLEKNVRAQLSTIESDEVTPDRRFRAR
VDDAIREGLKALGYYQPTIEFDLRPPPKKGRQVLIAKVTPGVPVLIGGTDVVLRGGARTD
KDYLKLLDTRPAIGTVLNQGDYENFKKSLTSIALRKGYFDSEFTKAQLGIALGLHKAFWD
IDYNSGERYRFGHVTFEGSQIRDEYLQNLVPFKEGDEYESKDLAELNRRLSATGWFNSVV
VAPQFDKARETKVLPLTGVVSPRTENTIETGVGYSTDVGPRVKATWKKPWMNSYGHSLTT
STSISAPEQTLDFSYKMPLLKNPLEQYYLVQGGFKRTDLNDTESDSTTLVASRYWDLSSG
WQRAINLRWSLDHFTQGEITNTTMLFYPGVMISRTRSRGGLMPTWGDSQRYSIDYSNTAW
GSDVDFSVFQAQNVWIRTLYDRHRFVTRGTLGWIETGDFDKVPPDLRFFAGGDRSIRGYK
YKSIAPKYANGDLKGASKLITGSLEYQYNVTGKWWGAVFVDSGEAVSDIRRSDFKTGTGV
GVRWESPVGPIKLDFAVPVADKDEHGLQFYIGLGPEL
References
External Links:
ResourceLink
Uniprot ID:P0ADE4
Uniprot Name:TAMA_ECOLI
PDB ID:2LY3
CCDB:TAMA_ECOLI
General Reference:Not Available