2.02012-10-10 13:28:11 -06002015-12-09 14:07:38 -0700ECMDB23274M2MDB003664DG(15:0/18:0/0:0)DG(15:0/18:0/0:0) belongs to the family of Diacylglycerols. These are glycerolipids lipids containing a common glycerol backbone to which at least one fatty acyl group is esterified. DG(15:0/18:0/0:0) is also a substrate of diacylglycerol kinase. It is involved in the phospholipid metabolic pathway.1-pentadecanoyl-2-octadecanoyl-sn-glycerol1-pentadecanoyl-2-stearoyl-sn-glycerolDAG(15:0/18:0)DAG(33:0)DG(15:0/18:0)DG(33:0)DiacylglycerolDiacylglycerol(15:0/18:0)Diacylglycerol(33:0)DiglycerideC36H70O5582.951582.522325354(2S)-2-hydroxy-3-(pentadecanoyloxy)propyl octadecanoate(2S)-2-hydroxy-3-(pentadecanoyloxy)propyl octadecanoate[H][C@](O)(COC(=O)CCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCCCCCInChI=1S/C36H70O5/c1-3-5-7-9-11-13-15-17-18-19-21-23-25-27-29-31-36(39)41-33-34(37)32-40-35(38)30-28-26-24-22-20-16-14-12-10-8-6-4-2/h34,37H,3-33H2,1-2H3/t34-/m0/s1LUQKIZTUDZZQSK-UMSFTDKQSA-NMembranelogp10.07logs-7.49solubility1.90e-05 g/llogp12.45pka_strongest_acidic13.63pka_strongest_basic-3.4iupac(2S)-2-hydroxy-3-(pentadecanoyloxy)propyl octadecanoateaverage_mass582.951mono_mass582.522325354smiles[H][C@](O)(COC(=O)CCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCCCCCformulaC36H70O5inchiInChI=1S/C36H70O5/c1-3-5-7-9-11-13-15-17-18-19-21-23-25-27-29-31-36(39)41-33-34(37)32-40-35(38)30-28-26-24-22-20-16-14-12-10-8-6-4-2/h34,37H,3-33H2,1-2H3/t34-/m0/s1inchikeyLUQKIZTUDZZQSK-UMSFTDKQSA-Npolar_surface_area72.83refractivity172.3polarizability78.1rotatable_bond_count35acceptor_count3donor_count1physiological_charge0formal_charge0phospholipid biosynthesis CDP-DG(15:0/18:0)Phospholipids are membrane components in E. coli. The major phospholipids of E. coli are phosphatidylethanolamine, phosphatidylglycerol and cardiolipin. All phospholipids contain sn-glycerol-3-phosphate esterified with fatty acids at the sn-1 and sn-2 positions. The reaction starts from a glycerone phosphate (dihydroxyacetone phosphate) produced in glycolysis. The glycerone phosphate is transformed to a sn-glycerol 3-phosphate (glycerol 3 phosphate) by NADPH driven glycerol-3-phosphate dehydrogenase. Sn-glycerol 3-phosphate is transformed to a 1-acyl-sn-glycerol 3-phosphate(1-oleyl-2-lyso-phosphatidate , 1-palmitoylglycerol 3-phosphate , 1-stearoyl-sn-glycerol 3-phosphate). This can be achieve by a sn-glycerol-3-phosphate 1-0-acyltransferase that interacts either with a long-chain acyl-CoA or with an acyl-[acp]. The 1-acyl-sn-glycerol 3-phosphate is transformed into a 1,2-diacyl-sn-glycerol 3-phosphate through a 1-acylglycerol-3-phosphate O-acyltransferase. This compound is then converted into a CPD-diacylglycerol through a CTP (phosphatidate cytididyltransferase. CPD-diacylglycerol can be transformed either to a PS (16:1(9z)/18:1(11z))L-1-phosphatidylserine or a L-1-phosphatidy PE(16:1(9z)/18:1(11z)) (phosphatidylethanolamine) through a phosphatidylserine decarboxylase, on the other hand PGP(16:1(9z)/18:1(11z)) L-1-phosphatidylglycerol-phosphate gets transformed into a PG(16:1(9z)/18:1(11z)) L-1-phosphatidyl-glycerol through a phosphatidylglycerophosphatase. These 2 products combines produce a cardiolipin and a ethanolamine. The L-1 phosphatidyl-glycerol can also interact with cardiolipin synthase resulting in a glycerol and a cardiolipin.PW001811MetabolicSpecdb::CMs49999Specdb::CMs282674Specdb::CMs405032Specdb::NmrOneD339128Specdb::NmrOneD339129Specdb::NmrOneD339130Specdb::NmrOneD339131Specdb::NmrOneD339132Specdb::NmrOneD339133Specdb::NmrOneD339134Specdb::NmrOneD339135Specdb::NmrOneD339136Specdb::NmrOneD339137Specdb::NmrOneD339138Specdb::NmrOneD339139Specdb::NmrOneD339140Specdb::NmrOneD339141Specdb::NmrOneD339142Specdb::NmrOneD339143Specdb::NmrOneD339144Specdb::NmrOneD339145Specdb::NmrOneD339146Specdb::NmrOneD339147Specdb::MsMs2329524Specdb::MsMs2329525Specdb::MsMs2329526Specdb::MsMs2636512Specdb::MsMs2636513Specdb::MsMs2636514HMDB07071Yurtsever D. (2007). Fatty acid methyl ester profiling of Enterococcus and Esherichia coli for microbial source tracking. M.sc. Thesis. Villanova University: U.S.APhosphatidylglycerophosphatase BP0A924PGPB_ECOLIpgpBhttp://ecmdb.ca/proteins/P0A924.xmlPhosphatidate cytidylyltransferaseP0ABG1CDSA_ECOLIcdsAhttp://ecmdb.ca/proteins/P0ABG1.xmlDiacylglycerol kinaseP0ABN1KDGL_ECOLIdgkAhttp://ecmdb.ca/proteins/P0ABN1.xmlDG(15:0/18:0/0:0) + Hydrogen ion + Cytidine triphosphate + DG(15:0/18:0/0:0) > CDP-DG(15:0/18:0) + PyrophosphatePW_R004799