Record Information
Version2.0
Creation Date2012-07-30 14:55:06 -0600
Update Date2015-06-03 17:21:00 -0600
Secondary Accession Numbers
  • ECMDB21246
Identification
Name:Molybdate
Description:Molybdate is a compound containing an oxoanion with molybdenum in its highest oxidation state of 6. Molybdenum can form a very large range of such oxoanions which can be discrete structures or polymeric extended structures, although the latter are only found in the solid state.The larger oxoanions are members of group of compounds termed polyoxometalates, and because they contain only one type of metal atom are often called isopolymetalates. The discrete molybdenum oxoanions range in size from the simplest MoO42_, found in potassium molybdate up to extremely large structures found in isopoly-molybdenum blues that contain for example 154 Mo atoms. The behaviour of molybdenum is different from the other elements in group 6. Molybdate is involved in the molybdenum cofactor biosynthesis pathway. Molybdate reacts with molybdopterin-AMP to produce molybdenum cofactor, AMP, and H2O.
Structure
Thumb
Synonyms:
  • Molybdate
  • Molybdate ion
  • Molybdates
  • Molybdic acid
  • Molybdic acid ion
  • MoO4-2
  • MoO42-
  • MoO4-2
  • MoO42-
  • Tetraoxidomolybdate(2)
  • Tetraoxidomolybdate(6)
  • Tetraoxidomolybdic acid(2)
  • Tetraoxidomolybdic acid(6)
  • [MoO4]2
Chemical Formula:H2MoO4
Weight:Average: 161.95
Monoisotopic: 163.900716398
InChI Key:VLAPMBHFAWRUQP-UHFFFAOYSA-L
InChI:InChI=1S/Mo.2H2O.2O/h;2*1H2;;/q+2;;;;/p-2
CAS number:14259-85-9
IUPAC Name:dioxomolybdenumdiol
Traditional IUPAC Name:molybdic acid
SMILES:O[Mo](O)(=O)=O
Chemical Taxonomy
DescriptionThis compound belongs to the class of chemical entities known as miscellaneous molybdates. These are inorganic compounds in which the largest metallic oxoanion is molybdate, to which either no atom or a non metal atom is bonded.
KingdomChemical entities
Super ClassInorganic compounds
ClassMixed metal/non-metal compounds
Sub ClassMiscellaneous mixed metal/non-metals
Direct ParentMiscellaneous molybdates
Alternative Parents
Substituents
  • Molybdate
  • Inorganic oxide
  • Inorganic salt
Molecular FrameworkNot Available
External Descriptors
Physical Properties
State:Solid
Charge:0
Melting point:Not Available
Experimental Properties:
PropertyValueSource
Predicted Properties
PropertyValueSource
logP-1.8ChemAxon
pKa (Strongest Acidic)12.08ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count4ChemAxon
Hydrogen Donor Count2ChemAxon
Polar Surface Area74.6 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity8.02 m3·mol-1ChemAxon
Polarizability6.51 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Biological Properties
Cellular Locations:Cytoplasm
Reactions:
SMPDB Pathways:
GTP degradationPW001888 Pw001888Pw001888 greyscalePw001888 simple
KEGG Pathways:
EcoCyc Pathways:
Concentrations
Not Available
Spectra
Spectra:
Spectrum TypeDescriptionSplash Key
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Positivesplash10-03di-0900000000-0c995c2675b9dc7328d3View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Positivesplash10-03di-0900000000-715bd2f482e6d6ae96e5View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Positivesplash10-03di-1900000000-b9657af70b38b252a964View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Negativesplash10-03di-0900000000-3430f802de06e4388b6cView in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Negativesplash10-03di-1900000000-7a625ca3fa73123682ebView in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Negativesplash10-03di-0900000000-823fafde4fdd7f6219c2View in MoNA
References
References:
  • Keseler, I. M., Collado-Vides, J., Santos-Zavaleta, A., Peralta-Gil, M., Gama-Castro, S., Muniz-Rascado, L., Bonavides-Martinez, C., Paley, S., Krummenacker, M., Altman, T., Kaipa, P., Spaulding, A., Pacheco, J., Latendresse, M., Fulcher, C., Sarker, M., Shearer, A. G., Mackie, A., Paulsen, I., Gunsalus, R. P., Karp, P. D. (2011). "EcoCyc: a comprehensive database of Escherichia coli biology." Nucleic Acids Res 39:D583-D590. Pubmed: 21097882
Synthesis Reference:Not Available
Material Safety Data Sheet (MSDS)Not Available
External Links:
ResourceLink
CHEBI ID36264
HMDB IDHMDB12260
Pubchem Compound ID24621
Kegg IDC06232
ChemSpider ID23023
WikipediaMolybdate
BioCyc IDCPD-3
EcoCyc IDCPD-3

Enzymes

General function:
Involved in nucleotide binding
Specific function:
Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system
Gene Name:
cysA
Uniprot ID:
P16676
Molecular weight:
41059
Reactions
ATP + H(2)O + sulfate(Out) = ADP + phosphate + sulfate(In).
General function:
Involved in transporter activity
Specific function:
Part of the ABC transporter complex cysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane
Gene Name:
cysW
Uniprot ID:
P0AEB0
Molecular weight:
32537
General function:
Involved in transporter activity
Specific function:
Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane
Gene Name:
modB
Uniprot ID:
P0AF01
Molecular weight:
24939
General function:
Involved in transporter activity
Specific function:
Part of the ABC transporter complex cysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane
Gene Name:
cysU
Uniprot ID:
P16701
Molecular weight:
30292
General function:
Involved in transporter activity
Specific function:
This protein specifically binds sulfate and is involved in its transmembrane transport
Gene Name:
sbp
Uniprot ID:
P0AG78
Molecular weight:
36659
General function:
Involved in Mo-molybdopterin cofactor biosynthetic process
Specific function:
Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP
Gene Name:
moeA
Uniprot ID:
P12281
Molecular weight:
44067
Reactions
Adenylyl-molybdopterin + molybdate = molybdenum cofactor + AMP.
General function:
Involved in transporter activity
Specific function:
Part of the ABC transporter complex cysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. This protein specifically binds thiosulfate and is involved in its transmembrane transport
Gene Name:
cysP
Uniprot ID:
P16700
Molecular weight:
37614
General function:
Involved in nucleotide binding
Specific function:
Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
Gene Name:
modC
Uniprot ID:
P09833
Molecular weight:
39102
Reactions
ATP + H(2)O + molybdate(Out) = ADP + phosphate + molybdate(In).
General function:
Involved in molybdate transmembrane-transporting ATPase activity
Specific function:
Involved in the transport of molybdenum into the cell. Binds molybdate with high specificity and affinity
Gene Name:
modA
Uniprot ID:
P37329
Molecular weight:
27364

Transporters

General function:
Involved in nucleotide binding
Specific function:
Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system
Gene Name:
cysA
Uniprot ID:
P16676
Molecular weight:
41059
Reactions
ATP + H(2)O + sulfate(Out) = ADP + phosphate + sulfate(In).
General function:
Involved in transporter activity
Specific function:
Part of the ABC transporter complex cysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane
Gene Name:
cysW
Uniprot ID:
P0AEB0
Molecular weight:
32537
General function:
Involved in transporter activity
Specific function:
Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane
Gene Name:
modB
Uniprot ID:
P0AF01
Molecular weight:
24939
General function:
Involved in transporter activity
Specific function:
Part of the ABC transporter complex cysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane
Gene Name:
cysU
Uniprot ID:
P16701
Molecular weight:
30292
General function:
Involved in transporter activity
Specific function:
This protein specifically binds sulfate and is involved in its transmembrane transport
Gene Name:
sbp
Uniprot ID:
P0AG78
Molecular weight:
36659
General function:
Involved in transporter activity
Specific function:
Non-specific porin
Gene Name:
ompN
Uniprot ID:
P77747
Molecular weight:
41220
General function:
Involved in transporter activity
Specific function:
Part of the ABC transporter complex cysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. This protein specifically binds thiosulfate and is involved in its transmembrane transport
Gene Name:
cysP
Uniprot ID:
P16700
Molecular weight:
37614
General function:
Involved in transporter activity
Specific function:
Uptake of inorganic phosphate, phosphorylated compounds, and some other negatively charged solutes
Gene Name:
phoE
Uniprot ID:
P02932
Molecular weight:
38922
General function:
Involved in transporter activity
Specific function:
OmpF is a porin that forms passive diffusion pores which allow small molecular weight hydrophilic materials across the outer membrane. It is also a receptor for the bacteriophage T2
Gene Name:
ompF
Uniprot ID:
P02931
Molecular weight:
39333
General function:
Involved in nucleotide binding
Specific function:
Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
Gene Name:
modC
Uniprot ID:
P09833
Molecular weight:
39102
Reactions
ATP + H(2)O + molybdate(Out) = ADP + phosphate + molybdate(In).
General function:
Involved in transporter activity
Specific function:
Forms passive diffusion pores which allow small molecular weight hydrophilic materials across the outer membrane
Gene Name:
ompC
Uniprot ID:
P06996
Molecular weight:
40368
General function:
Involved in molybdate transmembrane-transporting ATPase activity
Specific function:
Involved in the transport of molybdenum into the cell. Binds molybdate with high specificity and affinity
Gene Name:
modA
Uniprot ID:
P37329
Molecular weight:
27364