2.02012-05-31 14:32:23 -06002015-10-15 16:14:32 -0600ECMDB20192M2MDB001038Sedoheptulose 1,7-bisphosphateSedoheptulose 1,7-bisphosphate is a member of the chemical class known as Organophosphate Esters. These are organic compounds containing phosphoric acid ester functional group. Sedoheptulose-1,7-bisphosphate is invovled in the photosynthetic Calvin cycle. Sedoheptulose-1,7-bisphosphatase (SBPase) is an enzyme unique to photosynthetic organisms and has a key role in regulating the photosynthetic Calvin cycle through which nearly all carbon enters the biosphere. (PMID 9758762)D-Altro-Heptulose 1,7-biphosphateD-altro-Heptulose 1,7-biphosphoric acidD-Sedoheptulose 1,7-bisphosphateD-Sedoheptulose 1,7-bisphosphoric acidD-Sedoheptulose-1,7-bisphosphateD-Sedoheptulose-1,7-bisphosphoric acidD-Sedoheptulose-1,7-diphosphateD-Sedoheptulose-1,7-diphosphoric acidD-Sedoheptulose-1,7-P2D-sedoheptulose-1,7-P<SUB>2</SUB>D-SEDOHEPTULOSE-1-7-P2SBPSedoheptulose 1,7-bisphosphateSedoheptulose 1,7-bisphosphoric acidC7H16O13P2370.1417370.006613622{[3,4,5,6-tetrahydroxy-2-oxo-7-(phosphonooxy)heptyl]oxy}phosphonic acid[3,4,5,6-tetrahydroxy-2-oxo-7-(phosphonooxy)heptyl]oxyphosphonic acid815-91-8O[C@H](COP(O)(O)=O)[C@@H](O)[C@@H](O)[C@H](O)C(=O)COP(O)(O)=OInChI=1S/C7H16O13P2/c8-3(1-19-21(13,14)15)5(10)7(12)6(11)4(9)2-20-22(16,17)18/h3,5-8,10-12H,1-2H2,(H2,13,14,15)(H2,16,17,18)/t3-,5-,6-,7-/m1/s1OKHXOUGRECCASI-SHUUEZRQSA-NCytosollogp-1.52logs-1.41solubility1.43e+01 g/llogp-4.1pka_strongest_acidic1.01pka_strongest_basic-3.5iupac{[3,4,5,6-tetrahydroxy-2-oxo-7-(phosphonooxy)heptyl]oxy}phosphonic acidaverage_mass370.1417mono_mass370.006613622smilesO[C@H](COP(O)(O)=O)[C@@H](O)[C@@H](O)[C@H](O)C(=O)COP(O)(O)=OformulaC7H16O13P2inchiInChI=1S/C7H16O13P2/c8-3(1-19-21(13,14)15)5(10)7(12)6(11)4(9)2-20-22(16,17)18/h3,5-8,10-12H,1-2H2,(H2,13,14,15)(H2,16,17,18)/t3-,5-,6-,7-/m1/s1inchikeyOKHXOUGRECCASI-SHUUEZRQSA-Npolar_surface_area231.51refractivity65.27polarizability27.83rotatable_bond_count10acceptor_count11donor_count8physiological_charge-4formal_charge0Microbial metabolism in diverse environmentsec01120sedoheptulose bisphosphate bypassPWY0-1517Specdb::MsMs25268Specdb::MsMs25269Specdb::MsMs25270Specdb::MsMs31826Specdb::MsMs31827Specdb::MsMs3182811931156C0044717969D-SEDOHEPTULOSE-1-7-P2Keseler, I. M., Collado-Vides, J., Santos-Zavaleta, A., Peralta-Gil, M., Gama-Castro, S., Muniz-Rascado, L., Bonavides-Martinez, C., Paley, S., Krummenacker, M., Altman, T., Kaipa, P., Spaulding, A., Pacheco, J., Latendresse, M., Fulcher, C., Sarker, M., Shearer, A. G., Mackie, A., Paulsen, I., Gunsalus, R. P., Karp, P. D. (2011). "EcoCyc: a comprehensive database of Escherichia coli biology." Nucleic Acids Res 39:D583-D590.21097882Kanehisa, M., Goto, S., Sato, Y., Furumichi, M., Tanabe, M. (2012). "KEGG for integration and interpretation of large-scale molecular data sets." Nucleic Acids Res 40:D109-D114.22080510Dunford, R. P., Catley, M. A., Raines, C. A., Lloyd, J. C., Dyer, T. A. (1998). "Purification of active chloroplast sedoheptulose-1,7-bisphosphatase expressed in Escherichia coli." Protein Expr Purif 14:139-145.97587626-phosphofructokinase isozyme 1P0A796K6PF1_ECOLIpfkAhttp://ecmdb.ca/proteins/P0A796.xmlFructose-bisphosphate aldolase class 1P0A991ALF1_ECOLIfbaBhttp://ecmdb.ca/proteins/P0A991.xmlFructose-bisphosphate aldolase class 2P0AB71ALF_ECOLIfbaAhttp://ecmdb.ca/proteins/P0AB71.xmlSedoheptulose 1,7-bisphosphate <> Dihydroxyacetone phosphate + D-Erythrose 4-phosphateR01829SEDOBISALDOL-RXNAdenosine triphosphate + D-Sedoheptulose 7-phosphate > ADP + Hydrogen ion + Sedoheptulose 1,7-bisphosphateRXN0-6541Dihydroxyacetone phosphate + D-Erythrose 4-phosphate < Sedoheptulose 1,7-bisphosphateSEDOBISALDOL-RXN