2.02012-05-31 13:52:23 -06002015-09-13 12:56:11 -0600ECMDB01426M2MDB000382FormaldehydeFormaldehyde is a highly reactive aldehyde gas. It is the simplest aldehyde. Its chemical formula is H2CO. Although formaldehyde is a gas at room temperature, it is readily soluble in water, and it is most commonly sold as a 37% solution in water called by trade names such as formalin or formol. In water, formaldehyde polymerizes, and formalin actually contains very little formaldehyde in the form of H2CO monomer. Formaldehyde exhibits most of the general chemical properties of the aldehydes, except that is generally more reactive than other aldehydes. Formaldehyde is a potent electrophile. It can participate in electrophilic aromatic substitution reactions with aromatic compounds and can undergo electrophilic addition reactions with alkenes. In E. coli, formaldehyde is formed by the breakdown of N-methyltryptophan and FMNH by their corresponding oxidases.Aldeide formicaChlodithanChlodithaneFannoformFormaldehydeFormalinFormalinaFormalineFormalithFormic aldehydeFormolMethaldehydeMethanalMethylene glycolMethylene oxideOxomethyleneParaformCH2O30.02630.010564686formaldehydeformaldehyde50-00-0C=OInChI=1S/CH2O/c1-2/h1H2WSFSSNUMVMOOMR-UHFFFAOYSA-NLiquidCytosolExtra-organismPeriplasmlogp-0.68logs0.82solubility1.98e+02 g/lmelting_point-92 oClogp-0.47pka_strongest_basic-8.1iupacformaldehydeaverage_mass30.026mono_mass30.010564686smilesC=OformulaCH2OinchiInChI=1S/CH2O/c1-2/h1H2inchikeyWSFSSNUMVMOOMR-UHFFFAOYSA-Npolar_surface_area17.07refractivity6.31polarizability2.58rotatable_bond_count0acceptor_count1donor_count0physiological_charge0formal_charge0Methane metabolismec00680Microbial metabolism in diverse environmentsec01120Chloroalkane and chloroalkene degradationec00625formaldehyde oxidation II (glutathione-dependent)PWY-1801Specdb::CMs3285Specdb::CMs165347Specdb::EiMs1163Specdb::NmrOneD2400Specdb::NmrOneD4841Specdb::NmrOneD4842Specdb::NmrOneD147690Specdb::NmrOneD147691Specdb::NmrOneD147692Specdb::NmrOneD147693Specdb::NmrOneD147694Specdb::NmrOneD147695Specdb::NmrOneD147696Specdb::NmrOneD147697Specdb::NmrOneD147698Specdb::NmrOneD147699Specdb::MsMs10430Specdb::MsMs10431Specdb::MsMs10432Specdb::MsMs17102Specdb::MsMs17103Specdb::MsMs17104Specdb::MsMs3039089Specdb::MsMs3039090Specdb::MsMs3039091Specdb::MsMs3101888Specdb::MsMs3101889Specdb::MsMs3101890Specdb::NmrTwoD1070HMDB01426712692C0006716842FORMALDEHYDEFORFormaldehydeKeseler, I. 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Arch Pathol Lab Med. 1994 Jun;118(6):633-9.8204010http://hmdb.ca/system/metabolites/msds/000/001/288/original/HMDB01426.pdf?1358461418Catalase-peroxidaseP13029KATG_ECOLIkatGhttp://ecmdb.ca/proteins/P13029.xmlCatalase HPIIP21179CATE_ECOLIkatEhttp://ecmdb.ca/proteins/P21179.xmlPrimary amine oxidaseP46883AMO_ECOLItynAhttp://ecmdb.ca/proteins/P46883.xmlFMN reductaseP80644SSUE_ECOLIssuEhttp://ecmdb.ca/proteins/P80644.xmlAlkanesulfonate monooxygenaseP80645SSUD_ECOLIssuDhttp://ecmdb.ca/proteins/P80645.xmlN-methyl-L-tryptophan oxidaseP40874MTOX_ECOLIsolAhttp://ecmdb.ca/proteins/P40874.xmlAlpha-ketoglutarate-dependent dioxygenase AlkBP05050alkBhttp://ecmdb.ca/proteins/P05050.xmlOuter membrane protein NP77747OMPN_ECOLIompNhttp://ecmdb.ca/proteins/P77747.xmlOuter membrane pore protein EP02932PHOE_ECOLIphoEhttp://ecmdb.ca/proteins/P02932.xmlOuter membrane protein FP02931OMPF_ECOLIompFhttp://ecmdb.ca/proteins/P02931.xmlOuter membrane protein CP06996OMPC_ECOLIompChttp://ecmdb.ca/proteins/P06996.xmlFMNH + Methanesulfonate + Oxygen > Formaldehyde + Flavin Mononucleotide + Hydrogen ion + Water + SulfiteWater + Oxygen + Sarcosine > Formaldehyde + Glycine + Hydrogen peroxideN-Methyltryptophan + Water + Oxygen > Formaldehyde + Hydrogen peroxide + L-TryptophanRXN0-301Formaldehyde + Glutathione <> S-(Hydroxymethyl)glutathioneRXN-2961Methanol + Hydrogen peroxide <> Formaldehyde +2 WaterR00602Methylamine + Oxygen + Water <> Formaldehyde + Ammonia + Hydrogen peroxideR06154Formaldehyde + Tetrahydrofolic acid > 5,10-Methylene-THF + WaterRXN-2881a methylated nucleobase within DNA + Oxygen + Oxoglutaric acid Hydrogen ion + a nucleobase within DNA + Carbon dioxide + Formaldehyde + Succinic acidRXN-12353S-(Hydroxymethyl)glutathione <> Formaldehyde + GlutathioneRXN-2961N1-Methyladenine + Oxygen + Oxoglutaric acid > Hydrogen ion + Adenine + Carbon dioxide + Formaldehyde + Succinic acidRXN0-984N3-Methylcytosine + Oxygen + Oxoglutaric acid > Hydrogen ion + Cytosine + Carbon dioxide + Formaldehyde + Succinic acidRXN0-985DNA-base-CH(3) + Oxoglutaric acid + Oxygen > DNA-base + Formaldehyde + Succinic acid + Carbon dioxideN-methyl-L-tryptophan + Water + Oxygen > L-Tryptophan + Formaldehyde + Hydrogen peroxide